Biomarker Discovery Research Officer

About the role

MiRXES, a Singapore-headquartered molecular diagnostic company focused on microRNA technologies, is looking for a Research Officer to join its Profiling and Sequencing team at its Helios site. The biomarker team research officer helps develop and run protocols and standard operating procedures so that high-quality data can be obtained from clinical samples. The position is onsite in Singapore.

Key responsibilities

• Run experiments for high-throughput biomarker discovery using clinical samples.
• Perform miRNA RT-qPCR profiling, including RNA isolation, reverse transcription and qPCR.
• Carry out NGS workflows: nucleic acid extraction, library preparation and sequencing.
• Work with other technologies, whether commercially available or developed in-house.
• Keep accurate inventory of clinical samples and maintain experimental records.
• Search the literature, design and run experiments to develop, optimise and validate biomarker discovery technologies.
• Collect and organise data for downstream analysis.
• Run other experiments such as ELISA and Western blotting as needed.
• Support technical reports, SOPs and documents, and validate instrument testing and quality control procedures.
• Manage inventory and procurement of consumables and reagents, and support bio-banking activities such as blood processing and sample registration.
• Support compliance with health and safety policies.

Required profile

• Diploma or degree in a related science discipline.
• At least 2 to 4 years of molecular biology experience preferred.
• Results-oriented, with integrity, dependability and strong prioritisation.
• Able to troubleshoot technically, make sound decisions and plan ahead for contingencies.
• Good verbal communication, interpersonal and team skills; able to work independently and in a team in a fast-paced environment.

Required skills

• ELISA, NGS and RT-qPCR experience is a plus.

Only shortlisted candidates will be contacted.