Senior / Laboratory Executive - Spatial Biology Core

About the role

The Spatial Biology Core is a core facility within the Cancer Science Institute of Singapore, offering end-to-end tissue-based research support through bioimaging and spatial biology platforms. It is looking for a meticulous, service-oriented and technically capable Senior / Laboratory Executive to run the day-to-day spatial biology services, covering sample processing, assay execution, imaging and image analysis, as well as purchasing, billing support, service documentation and safety record keeping.

Key responsibilities

• Serve as the primary operator for spatial transcriptomics services, including the Digital Spatial Profiler and nCounter platforms
• Assist with PhenoCycler and multiplexed immunohistochemistry services, including image analysis when required
• Work with the Facility Manager to evaluate, incorporate and optimise workflows for new spatial transcriptomics platforms
• Prepare, update and maintain technical documentation, protocols and workflow guides
• Provide user training and technical support, and help with troubleshooting, quality control and continuous improvement
• Coordinate and renew service contracts for spatial biology equipment
• Assist with purchasing reagents, consumables and equipment
• Maintain safety documentation, SOPs and risk assessments, and keep records of services rendered and equipment use
• Support billing and other facility administration, and carry out ad hoc duties

Required profile

• Bachelor's degree in Life Sciences, Biomedical Sciences, Biochemistry, Pharmaceutical Sciences or a related discipline
• Understanding of immunology, molecular biology, cancer biology, medicine or bioinformatics
• Experience with traditional spatial biology techniques such as immunohistochemistry or RNAscope
• Familiarity with basic histology workflows, including FFPE block preparation and tissue sectioning
• Excellent multitasking ability, able to work independently and collaboratively under pressure

Required skills

• Advantageous: experience with Bruker Digital Spatial Profiler, Quanterix PhenoCycler / PhenoImager, 10x Genomics Visium / Xenium or similar platforms
• Highly regarded: image analysis software such as inForm, Visiopharm or QuPath
• Proficiency in Microsoft Word, Excel and PowerPoint
• Advantageous: knowledge of histology and anatomy, experience supporting users or training junior staff, and use of AI tools for documentation, data analysis or workflow optimisation