Senior Scientist (Immunoassay)

About the role

Labcorp is seeking a Senior Scientist - Immunochemistry to join its team in Singapore. The role covers the development, optimization, qualification, validation, troubleshooting and execution of complex bioanalytical assays supporting nonclinical and clinical drug development. It requires deep expertise in cell-based neutralizing antibody (NAb) assays and/or flow cytometry, and the scientist acts as a subject matter expert for assay design, data interpretation and regulatory compliance.

Key responsibilities

• Serve as a subject matter expert in cell-based immunogenicity assays, especially neutralizing antibody (NAb) assays.
• Lead the design, development, optimization, qualification, transfer and validation of bioanalytical methods.
• Troubleshoot complex assay performance, data quality and platform issues.
• Design and validate multicolor flow cytometry assays for pharmacokinetics, biomarkers and functional cell-based applications, including staining panels, gating strategies, controls and data analysis.
• Analyze and interpret flow cytometry datasets and support evaluation of new flow cytometry methodologies.
• Oversee regulated bioanalytical studies, review raw data and study results, and investigate assay deviations and laboratory incidents.
• Work in line with SOPs and quality systems, and comply with GLP, GCP or other regulated environments where applicable.
• Take part in audits, inspections and client interactions as a technical representative, and prepare and review study reports, validation reports, SOPs and protocols.
• Mentor scientists and analysts, and collaborate with Study Directors, Principal Investigators, Project Managers, Quality Assurance and clients.

Required profile

• Bachelor's degree with extensive relevant experience in bioanalytical sciences.
• Preferred: Master's degree in Immunology, Cell Biology, Biochemistry, Pharmaceutical Sciences or a related discipline, with 5+ years of relevant industry experience or equivalent experience in a pharmaceutical, biotechnology, CRO or regulated laboratory setting.
• Experience with biologics, cell and gene therapies, vaccines or other advanced therapeutics is desirable.

Required skills

• Hands-on experience in cell-based neutralizing antibody (NAb) assays (highly preferred).
• Hands-on experience in flow cytometry assay development and data analysis (highly preferred).
• Assay validation, qualification and method transfer experience.
• Experience in GLP, GCP or other regulated environments is a strong plus.