Research Fellow / Senior Research Fellow – Mitochondrial Micropeptide Discovery
ntu · Singapore
Job description
About the role
The Lee Kong Chian School of Medicine (LKCMedicine) at Nanyang Technological University seeks a Research Fellow or Senior Research Fellow to lead a project focused on discovering and functionally validating novel mitochondria‑derived micropeptides that regulate energy expenditure in adipose tissue.
Key responsibilities
- Conceptualise, plan and execute the research project from hypothesis generation to data interpretation.
- Identify novel translated open reading frames in the mitochondrial genome across multiple mouse and human adipocyte models.
- Develop and apply an integrative proteogenomics workflow combining ribosome profiling, mass spectrometry and bioinformatic analyses.
- Characterise the functional impact of identified micropeptides on adipose tissue metabolism and systemic energy homeostasis.
- Collaborate with interdisciplinary teams and communicate findings through reports and scientific publications.
Required profile
- PhD or equivalent experience in molecular biology, biochemistry, or a related life‑science field.
- Demonstrated track record of independent research in proteomics, genomics or metabolic biology.
- Strong analytical mindset with the ability to design and troubleshoot complex experimental pipelines.
Required skills
- Ribosome profiling
- Proteogenomics
- Bioinformatics data analysis
- Molecular biology techniques
- Experience with mouse and human adipocyte cellular models
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Published 6 days ago
Expires 1 month from now
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ntu
Singapore
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