Manufacturing Senior Technician / Technician

About the role

AstraZeneca is building its first biologics manufacturing campus in Singapore, a USD 1.5 billion investment covering small-molecule chemical API production, large-molecule monoclonal antibody manufacturing, conjugation, sterile fill-and-finish and final secondary packaging. The role is a hands-on manufacturing technician position supporting safe, compliant and efficient production in this new facility.

Key responsibilities

• Run manufacturing activities according to approved electronic batch records, SOPs, permits, cGMP, data integrity and safety, health and environmental requirements; operate equipment and control systems within approved ranges and call out deviations, alarms and quality risks.
• Verify equipment status, calibration, materials, labels, utilities and documentation before processing, and carry out transfers, sampling, cleaning and changeover.
• Maintain accurate contemporaneous manufacturing records and electronic entries, and support shift coordination, work allocation, priorities and handovers under the Shift Team Lead.
• Report discrepancies, take part in investigations and root-cause analysis, and support CAPAs, change controls, risk assessments, validation and inspection readiness.
• Perform first-line troubleshooting, collaborate with Quality, Engineering, MS&T and Safety, and contribute to continuous improvement using lean and structured problem-solving tools.
• Support operational readiness, SOP development, batch record input, equipment setup, line readiness and material flow review, and support FAT, SAT, commissioning, qualification and validation of manufacturing and containment equipment.

Required profile

• Bachelor's degree or working towards a professional qualification, or a High School/Technical/Associate/Vocational diploma with equivalent experience.
• Demonstrated commitment to safety, quality and delivery in a regulated manufacturing environment, with a safety-first attitude.
• Strong written and verbal communication skills and good attention to detail.
• Desirable: experience in pharma/biopharma GMP manufacturing, equipment troubleshooting, and ADC, high-containment, high-potency or aseptic manufacturing.

Required skills

• Good understanding of GMP documentation, deviation management, change control, CAPA and equipment lifecycle management.
• Desirable: experience with Emerson DeltaV, Veeva QualityDocs, SAP, Siemens PLCs, and structured problem solving, root cause analysis or Lean Six Sigma.

The role involves in-person work, on average at least three days per week from the office, with some flexibility. The closing date is 28 October 2026.