Senior Research Fellow – Bioinformatics & Microbiome

About the role

We are seeking a motivated Senior Research Fellow to join the Centre for Microbiome Medicine at LKCMedicine, NTU Singapore. The role focuses on bioinformatics-driven investigations of microbiome‑host interactions, with an emphasis on colorectal cancer and metabolic disorders.

Key responsibilities

• Perform bioinformatics analysis of microbiome‑related omics data, including metagenomic and metatranscriptomic sequencing.
• Generate taxonomic profiles, functional annotations and reconstruct metagenome‑assembled genomes (MAGs).
• Integrate microbiome datasets with host genomics, metabolomics and clinical information to uncover biological insights.
• Develop and implement novel algorithms for multi‑omics data analysis.
• Lead independent research projects, collaborate with multidisciplinary teams, and present findings at scientific meetings.
• Prepare and submit grant applications to support ongoing and future research initiatives.

Required profile

• Academic background in Bioinformatics, Computational Biology or a related discipline.
• Strong interest in molecular microbiology and translational research.
• Proven ability to conduct independent research and work collaboratively.
• Excellent scientific communication skills for publications and presentations.

Required skills

• Bioinformatics analysis of metagenomic and metatranscriptomic data.
• Taxonomic profiling and functional annotation.
• Reconstruction of metagenome‑assembled genomes (MAGs).
• Integration of multi‑omics (metagenomics, metatranscriptomics, metabolomics) with host genomic and clinical data.
• Algorithm development for data analysis.